Zoonomia - Volume I Part 5
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Volume I Part 5

OF STIMULUS, SENSORIAL EXERTION, AND FIBROUS CONTRACTION.

I. Of fibrous contraction. 1. _Two particles of a fibre cannot approach without the intervention of something, as in magnetism, electricity, elasticity. Spirit of life is not electric ether. Galvani's experiments._ 2. _Contraction of a fibre._ 3. _Relaxation succeeds._ 4.

_Successive contractions, with intervals. Quick pulse from debility, from paucity of blood. Weak contractions performed in less time, and with shorter intervals._ 5. _Last situation of the fibres continues after contraction._ 6. _Contraction greater than usual induces pleasure or pain._ 7. _Mobility of the fibres uniform. Quant.i.ty of sensorial power fluctuates. Const.i.tutes excitability._ II. Of sensorial exertion.

1. _Animal motion includes stimulus, sensorial power, and contractile fibres. The sensorial faculties act separately or conjointly. Stimulus of four kinds. Strength and weakness defined. Sensorial power perpetually exhausted and renewed. Weakness from defect of stimulus.

From defect of sensorial power, the direct and indirect debility of Dr.

Brown. Why we become warm in Buxton bath after a time, and see well after a time in a darkish room. Fibres may act violently, or with their whole force, and yet feebly. Great exertion in inflammation explained.

Great muscular force of some insane people._ 2. _Occasional acc.u.mulation of sensorial power in muscles subject to constant stimulus. In animals sleeping in winter. In eggs, seeds, schirrous tumours, tendons, bones._ 3. _Great exertion introduces pleasure or pain. Inflammation. Libration of the system between torpor and activity. Fever-fits._ 4. _Desire and aversion introduced. Excess of volition cures fevers._ III. Of repeated stimulus. 1. _A stimulus repeated too frequently looses effect. As opium, wine, grief. Hence old age. Opium and aloes in small doses._ 2. _A stimulus not repeated too frequently does not lose effect. Perpetual movement of the vital organs._ 3. _A stimulus repeated at uniform times produces greater effect. Irritation combined with a.s.sociation._ 4. _A stimulus repeated frequently and uniformly may be withdrawn, and the action of the organ will continue. Hence the bark cures agues, and strengthens weak const.i.tutions._ 5. _Defect of stimulus repeated at certain intervals causes fever-fits._ 6. _Stimulus long applied ceases to act a second time._ 7. _If a stimulus excites sensation in an organ not usually excited into sensation, inflammation is produced._ IV. Of stimulus greater than natural. 1. _A stimulus greater than natural diminishes the quant.i.ty of sensorial power in general._ 2. _In particular organs._ 3. _Induces the organ into spasmodic actions._ 4. _Induces the antagonist fibres into action._ 5. _Induces the organ into convulsive or fixed spasms._ 6. _Produces paralysis of the organ._ V. Of stimulus less than natural. 1. _Stimulus less than natural occasions acc.u.mulation of sensorial power in general._ 2. _In particular organs, flushing of the face in a frosty morning. In fibres subject to perpetual stimulus only. Quant.i.ty of sensorial power inversely as the stimulus._ 3. _Induces pain. As of cold, hunger, head-ach._ 4. _Induces more feeble and frequent contraction. As in low fevers. Which are frequently owing to deficiency of sensorial power rather than to deficiency of stimulus._ 5. _Inverts successive trains of motion.

Inverts ideas._ 6. _Induces paralysis and death._ VI. Cure of increased exertion. 1. _Natural cure of exhaustion of sensorial power._ 2.

_Decrease the irritations. Venesection. Cold. Abstinence._ 3. _Prevent the previous cold fit. Opium. Bark. Warmth. Anger. Surprise._ 4.

_Excite some other part of the system. Opium and warm bath relieve pains both from defect and from excess of stimulus._ 5. _First increase the stimulus above, and then decrease it beneath the natural quant.i.ty._ VII. Cure of decreased exertion. 1. _Natural cure by acc.u.mulation of sensorial power. Ague-fits. Syncope._ 2. _Increase the stimulation, by wine, opium, given so as not to intoxicate. Cheerful ideas._ 3. _Change the kinds of stimulus._ 4. _Stimulate the a.s.sociated organs. Blisters of use in heart-burn, and cold extremities._ 5. _Decrease the stimulation for a time, cold bath._ 6. _Decrease the stimulation below natural, and then increase it above natural. Bark after emetics. Opium after venesection. Practice of Sydenham in chlorosis._ 7. _Prevent unnecessary expenditure of sensorial power. Dec.u.mbent posture, silence, darkness. Pulse quickened by rising out of bed._ 8. _To the greatest degree of quiescence apply the least stimulus. Otherwise paralysis or inflammation of the organ ensues. Gin, wine, blisters, destroy by too great stimulation in fevers with debility. Intoxication in the slightest degree succeeded by debility. Golden rule for determining the best degree of stimulus in low fevers. Another golden rule for determining the quant.i.ty of spirit which those, who are debilitated by drinking it, may safely omit._

I. _Of fibrous contraction._

1. If two particles of iron lie near each other without motion, and afterwards approach each other; it is reasonable to conclude that something besides the iron particles is the cause of their approximation; this invisible something is termed magnetism. In the same manner, if the particles, which compose an animal muscle, do not touch each other in the relaxed state of the muscle, and are brought into contact during the contraction of the muscle, it is reasonable to conclude, that some other agent is the cause of this new approximation. For nothing can act, where it does not exist; for to act includes to exist; and therefore the particles of the muscular fibre (which in its state of relaxation are supposed not to touch) cannot affect each other without the influence of some intermediate agent; this agent is here termed the spirit of animation, or sensorial power, but may with equal propriety be termed the power, which causes contraction; or may be called by any other name, which the reader may choose to affix to it.

The contraction of a muscular fibre may be compared to the following electric experiment, which is here mentioned not as a philosophical a.n.a.logy, but as an ill.u.s.tration or simile to facilitate the conception of a difficult subject. Let twenty very small Leyden phials properly coated be hung in a row by fine silk threads at a small distance from each other; let the internal charge of one phial be positive, and of the other negative alternately, if a communication be made from the internal surface of the first to the external surface of the last in the row, they will all of them instantly approach each other, and thus shorten a line that might connect them like a muscular fibre. See Botanic Garden, p. 1. Canto I. 1. 202, note on Gymnotus.

The attractions of electricity or of magnetism do not apply philosophically to the ill.u.s.tration of the contraction of animal fibres, since the force of those attractions increases in some proportion inversely as the distance, but in muscular motion there appears no difference in velocity or strength during the beginning or end of the contraction, but what may be clearly ascribed to the varying mechanic advantage in the approximation of one bone to another. Nor can muscular motion be a.s.similated with greater plausibility to the attraction of cohesion or elasticity; for in bending a steel spring, as a small sword, a less force is required to bend it the first inch than the second; and the second than the third; the particles of steel on the convex side of the bent spring endeavouring to restore themselves more powerfully the further they are drawn from each other. See Botanic Garden, P. I. addit. Note XVIII.

I am aware that this may be explained another way, by supposing the elasticity of the spring to depend more on the compression of the particles on the concave side than on the extension of them on the convex side; and by supposing the elasticity of the elastic gum to depend more on the resistance to the lateral compression of its particles than to the longitudinal extension of them. Nevertheless in muscular contraction, as above observed, there appears no difference in the velocity or force of it at its commencement or at its termination; from whence we must conclude that animal contraction is governed by laws of its own, and not by those of mechanics, chemistry, magnetism, or electricity.

On these accounts I do not think the experiments conclusive, which were lately published by Galvani, Volta, and others, to shew a similitude between the spirit of animation, which contracts the muscular fibres, and the electric fluid. Since the electric fluid may act only as a more potent stimulus exciting the muscular fibres into action, and not by supplying them with a new quant.i.ty of the spirit of life. Thus in a recent hemiplegia I have frequently observed, when the patient yawned and stretched himself, that the paralytic limbs moved also, though they were totally disobedient to the will. And when he was electrified by pa.s.sing shocks from the affected hand to the affected foot, a motion of the paralytic limbs was also produced. Now as in the act of yawning the muscles of the paralytic limbs were excited into action by the stimulus of the irksomeness of a continued posture, and not by any additional quant.i.ty of the spirit of life; so we may conclude, that the pa.s.sage of the electric fluid, which produced a similar effect, acted only as a stimulus, and not by supplying any addition of sensorial power.

If nevertheless this theory should ever become established, a stimulus must be called an eductor of vital ether; which stimulus may consist of sensation or volition, as in the electric eel, as well as in the appulses of external bodies; and by drawing off the charges of vital fluid may occasion the contraction or motions of the muscular fibres, and organs of sense.

2. The immediate effect of the action of the spirit of animation or sensorial power on the fibrous parts of the body, whether it acts in the mode of irritation, sensation, volition, or a.s.sociation, is a contraction of the animal fibre, according to the second law of animal causation. Sect.

IV. Thus the stimulus of the blood induces the contraction of the heart; the agreeable taste of a strawberry produces the contraction of the muscles of deglut.i.tion; the effort of the will contracts the muscles, which move the limbs in walking; and by a.s.sociation other muscles of the trunk are brought into contraction to preserve the balance of the body. The fibrous extremities of the organs of sense have been shewn, by the ocular spectra in Sect. III. to suffer similar contraction by each of the above modes of excitation; and by their configurations to const.i.tute our ideas.

3. After animal fibres have for some time been excited into contraction, a relaxation succeeds, even though the exciting cause continues to act. In respect to the irritative motions this is exemplified in the peristaltic contractions of the bowels; which cease and are renewed alternately, though the stimulus of the aliment continues to be uniformly applied; in the sensitive motions, as in strangury, tenesmus, and parturition, the alternate contractions and relaxations of the muscles exist, though the stimulus is perpetual. In our voluntary exertions it is experienced, as no one can hang long by the hands, however vehemently he wills so to do; and in the a.s.sociate motions the constant change of our att.i.tudes evinces the necessity of relaxation to those muscles, which have been long in action.

This relaxation of a muscle after its contraction, even though the stimulus continues to be applied, appears to arise from the expenditure or diminution of the spirit of animation previously resident in the muscle, according to the second law of animal causation in Sect. IV. In those const.i.tutions, which are termed weak, the spirit of animation becomes sooner exhausted, and tremulous motions are produced, as in the hands of infirm people, when they lift a cup to their mouths. This quicker exhaustion of the spirit of animation is probably owing to a less quant.i.ty of it residing in the acting fibres, which therefore more frequently require a supply from the nerves, which belong to them.

4. If the sensorial power continues to act, whether it acts in the mode of irritation, sensation, volition, or a.s.sociation, a new contraction of the animal fibre succeeds after a certain interval; which interval is of shorter continuance in weak people than in strong ones. This is exemplified in the shaking of the hands of weak people, when they attempt to write. In a ma.n.u.script epistle of one of my correspondents, which is written in a small hand, I observed from four to six zigzags in the perpendicular stroke of every letter, which shews that both the contractions of the fingers, and intervals between them, must have been performed in very short periods of time.

The times of contraction of the muscles of enfeebled people being less, and the intervals between those contractions being less also, accounts for the quick pulse in fevers with debility, and in dying animals. The shortness of the intervals between one contraction and another in weak const.i.tutions, is probably owing to the general deficiency of the quant.i.ty of the spirit of animation, and that therefore there is a less quant.i.ty of it to be received at each interval of the activity of the fibres. Hence in repeated motions, as of the fingers in performing on the harpsichord, it would at first sight appear, that swiftness and strength were incompatible; nevertheless the single contraction of a muscle is performed with greater velocity as well as with greater force by vigorous const.i.tutions, as in throwing a javelin.

There is however another circ.u.mstance, which may often contribute to cause the quickness of the pulse in nervous fevers, as in animals bleeding to death in the slaughter-house; which is the deficient quant.i.ty of blood; whence the heart is but half distended, and in consequence sooner contracts. See Sect. x.x.xII. 2. 1.

For we must not confound frequency of repet.i.tion with quickness of motion, or the number of pulsations with the velocity, with which the fibres, which const.i.tute the coats of the arteries, contract themselves. For where the frequency of the pulsations is but seventy-five in a minute, as in health; the contracting fibres, which const.i.tute the sides of the arteries, may move through a greater s.p.a.ce in a given time, than where the frequency of pulsation is one hundred and fifty in a minute, as in some fevers with great debility. For if in those fevers the arteries do not expand themselves in their diastole to more than half the usual diameter of their diastole in health, the fibres which const.i.tute their coats, will move through a less s.p.a.ce in a minute than in health, though they make two pulsations for one.

Suppose the diameter of the artery during its systole to be one line, and that the diameter of the same artery during its diastole is in health is four lines, and in a fever with, great debility only two lines. It follows, that the arterial fibres contract in health from a circle of twelve lines in circ.u.mference to a circle of three lines in circ.u.mference, that is they move through a s.p.a.ce of nine lines in length. While the arterial fibres in the fever with debility would twice contract from a circle of six lines to a circle of three lines; that is while they move through a s.p.a.ce equal to six lines. Hence though the frequency of pulsation in fever be greater as two to one, yet the velocity of contraction in health is greater as nine to six, or as three to two.

On the contrary in inflammatory diseases with strength, as in the pleurisy, the velocity of the contracting sides of the arteries is much greater than in health, for if we suppose the number of pulsations in a pleurisy to be half as much more than in health, that is as one hundred and twenty to eighty, (which is about what generally happens in inflammatory diseases) and if the diameter of the artery in diastole be one third greater than in health, which I believe is near the truth, the result will be, that the velocity of the contractile sides of the arteries will be in a pleurisy as two and a half to one, compared to the velocity of their contraction in a state of health, for if the circ.u.mference of the systole of the artery be three lines, and the diastole in health be twelve lines in circ.u.mference, and in a pleurisy eighteen lines; and secondly, if the artery pulsates thrice in the diseased state for twice in the healthy one, it follows, that the velocity of contraction in the diseased state to that in the healthy state will be forty-five to eighteen, or as two and a half to one.

From hence it would appear, that if we had a criterion to determine the velocity of the arterial contractions, it would at the same time give us their strength, and thus be of more service in distinguishing diseases, than the knowledge of their frequency. As such a criterion cannot be had, the frequency of pulsation, the age of the patient being allowed for, will in some measure a.s.sist us to distinguish arterial strength from arterial debility, since in inflammatory diseases with strength the frequency seldom exceeds one hundred and eighteen or one hundred and twenty pulsations in a minute; unless under peculiar circ.u.mstance, as the great additional stimuli of wine or of external heat.

5. After a muscle or organ of sense has been excited into contraction, and the sensorial power ceases to act, the last situation or configuration of it continues; unless it be disturbed by the action of some antagonist fibres, or other extraneous power. Thus in weak or languid people, wherever they throw their limbs on their bed or sofa, there they lie, till another exertion changes their att.i.tude; hence one kind of ocular spectra seems to be produced after looking at bright objects; thus when a fire-stick is whirled round in the night, there appears in the eye a complete circle of fire; the action or configuration of one part of the retina not ceasing before the return of the whirling fire.

Thus if any one looks at the setting sun for a short time, and then covers his closed eyes with his hand, he will for many seconds of time perceive the image of the sun on his retina. A similar image of all other bodies would remain some time in the eye, but is effaced by the eternal change of the motions of the extremity of this nerve in our attention to other objects. See Sect. XVIII. 5. on Sleep. Hence the dark spots, and other ocular spectra, are more frequently attended to, and remain longer in the eyes of weak people, as after violent exercise, intoxication, or want of sleep.

6. A contraction of the fibres somewhat greater than usual introduces pleasurable sensation into the system, according to the fourth law of animal causation. Hence the pleasure in the beginning of drunkenness is owing to the increased action of the system from the stimulus of vinous spirit or of opium. If the contractions be still greater in energy or duration, painful sensations are introduced, as in consequence of great heat, or caustic applications, or fatigue.

If any part of the system, which is used to perpetual activity, as the stomach, or heart, or the fine vessels of the skin, acts for a time with less energy, another kind of painful sensation ensues, which is called hunger, or faintness, or cold. This occurs in a less degree in the locomotive muscles, and is called wearysomeness. In the two former kinds of sensation there is an expenditure of sensorial power, in these latter there is an acc.u.mulation of it.

7. We have used the words exertion of sensorial power as a general term to express either irritation, sensation, volition, or a.s.sociation; that is, to express the activity or motion of the spirit of animation, at the time it produces the contractions of the fibrous parts of the system. It may be supposed that there may exist a greater or less mobility of the fibrous parts of our system, or a propensity to be stimulated into contraction by the greater or less quant.i.ty or energy of the spirit of animation; and that hence if the exertion of the sensorial power be in its natural state, and the mobility of the fibres be increased, the same quant.i.ty of fibrous contraction will be caused, as if the mobility of the fibres continues in its natural state, and the sensorial exertion be increased.

Thus it may be conceived, that in diseases accompanied with strength, as in inflammatory fevers with arterial strength, that the cause of greater fibrous contraction, may exist in the increased mobility of the fibres, whose contractions are thence both more forceable and more frequent. And that in diseases attended with debility, as in nervous fevers, where the fibrous contractions are weaker, and more frequent, it may be conceived that the cause consists in a decrease of mobility of the fibres; and that those weak const.i.tutions, which are attended with cold extremities and large pupils of the eyes, may possess less mobility of the contractile fibres, as well as less quant.i.ty of exertion of the spirit of animation.

In answer to this mode of reasoning it may be sufficient to observe, that the contractile fibres consist of inert matter, and when the sensorial power is withdrawn, as in death, they possess no power of motion at all, but remain in their last state, whether of contraction or relaxation, and must thence derive the whole of this property from the spirit of animation.

At the same time it is not improbable, that the moving fibres of strong people may possess a capability of receiving or containing a greater quant.i.ty of the spirit of animation than those of weak people.

In every contraction of a fibre there is an expenditure of the sensorial power, or spirit of animation; and where the exertion of this sensorial power has been for some time increased, and the muscles or organs of sense have in consequence acted with greater energy, its propensity to activity is proportionally lessened; which is to be ascribed to the exhaustion or diminution of its quant.i.ty. On the contrary, where there has been less fibrous contraction than usual for a certain time, the sensorial power or spirit of animation becomes acc.u.mulated in the inactive part of the system.

Hence vigour succeeds rest, and hence the propensity to action of all our organs of sense and muscles is in a state of perpetual fluctuation. The irritability for instance of the retina, that is, its quant.i.ty of sensorial power, varies every moment according to the brightness or obscurity of the object last beheld compared with the present one. The same occurs to our sense of heat, and to every part of our system, which is capable of being excited into action.

When this variation of the exertion of the sensorial power becomes much and permanently above or beneath the natural quant.i.ty, it becomes a disease. If the irritative motions be too great or too little, it shews that the stimulus of external things affect this sensorial power too violently or too inertly. If the sensitive motions be too great or too little, the cause arises from the deficient or exuberant quant.i.ty of sensation produced in consequence of the motions of the muscular fibres or organs of sense; if the voluntary actions are diseased the cause is to be looked for in the quant.i.ty of volition produced in consequence of the desire or aversion occasioned by the painful or pleasurable sensations above mentioned. And the diseases of a.s.sociations probably depend on the greater or less quant.i.ty of the other three sensorial powers by which they were formed.

From whence it appears that the propensity to action, whether it be called irritability, sensibility, voluntarity, or a.s.sociability, is only another mode of expression for the quant.i.ty of sensorial power residing in the organ to be excited. And that on the contrary the words inirritability and insensibility, together with inapt.i.tude to voluntary and a.s.sociate motions, are synonymous with deficiency of the quant.i.ty of sensorial power, or of the spirit of animation, residing in the organs to be excited.

II. _Of sensorial Exertion._

1. There are three circ.u.mstances to be attended to in the production of animal motions, 1st. The stimulus. 2d. The sensorial power. 3d. The contractile fibre. 1st. A stimulus, external to the organ, originally induces into action the sensorial faculty termed irritation; this produces the contraction of the fibres, which, if it be perceived at all, introduces pleasure or pain; which in their active state are termed sensation; which is another sensorial faculty, and occasionally produces contraction of the fibres; this pleasure or pain is therefore to be considered as another stimulus, which may either act alone or in conjunction with the former faculty of the sensorium termed irritation.

This new stimulus of pleasure or pain either induces into action the sensorial faculty termed sensation, which then produces the contraction of the fibres; or it introduces desire or aversion, which excite into action another sensorial faculty, termed volition, and may therefore be considered as another stimulus, which either alone or in conjunction with one or both of the two former faculties of the sensorium produces the contraction of animal fibres. There is another sensorial power, that of a.s.sociation, which perpetually, in conjunction with one or more of the above, and frequently singly, produces the contraction of animal fibres, and which is itself excited into action by the previous motions of contracting fibres.

Now as the sensorial power, termed irritation, residing in any particular fibres, is excited into exertion by the stimulus of external bodies acting on those fibres; the sensorial power, termed sensation, residing in any particular fibres is excited into exertion by the stimulus of pleasure or pain acting on those fibres; the sensorial power, termed volition, residing in any particular fibres is excited into exertion by the stimulus of desire or aversion; and the sensorial power, termed a.s.sociation, residing in any particular fibres, is excited into action by the stimulus of other fibrous motions, which had frequently preceded them. The word stimulus may therefore be used without impropriety of language, for any of these four causes, which excite the four sensorial powers into exertion. For though the immediate cause of volition has generally been termed _a motive_; and that of irritation only has generally obtained the name of _stimulus_; yet as the immediate cause, which excites the sensorial powers of sensation, or of a.s.sociation into exertion, have obtained no general name, we shall use the word stimulus for them all.

Hence the quant.i.ty of motion produced in any particular part of the animal system will be as the quant.i.ty of stimulus and the quant.i.ty of sensorial power, or spirit of animation, residing in the contracting fibres. Where both these quant.i.ties are great, _strength_ is produced, when that word is applied to the motions of animal bodies. Where either of them is deficient, _weakness_ is produced, as applied to the motions of animal bodies.

Now as the sensorial power, or spirit of animation, is perpetually exhausted by the expenditure of it in fibrous contractions, and is perpetually renewed by the secretion or production of it in the brain and spinal marrow, the quant.i.ty of animal strength must be in a perpetual state of fluctuation on this account; and if to this be added the unceasing variation of all the four kinds of stimulus above described, which produce the exertions of the sensorial powers, the ceaseless vicissitude of animal strength becomes easily comprehended.

If the quant.i.ty of sensorial power remains the same, and the quant.i.ty of stimulus be lessened, a weakness of the fibrous contractions ensues, which may be denominated _debility from defect of stimulus_. If the quant.i.ty of stimulus remains the same, and the quant.i.ty of sensorial power be lessened, another kind of weakness ensues, which may be termed _debility from defect of sensorial power_; the former of these is called by Dr. Brown, in his Elements of Medicine, direct debility, and the latter indirect debility.

The coincidence of some parts of this work with correspondent deductions in the Brunonian Elementa Medicina, a work (with some exceptions) of great genius, must be considered as confirmations of the truth of the theory, as they were probably arrived at by different trains of reasoning.

Thus in those who have been exposed to cold and hunger there is a deficiency of stimulus. While in nervous fever there is a deficiency of sensorial power. And in habitual drunkards, in a morning before their usual potation, there is a deficiency both of stimulus and of sensorial power.

While, on the other hand, in the beginning of intoxication there is an excess of stimulus; in the hot-ach, after the hands have been immersed in snow, there is a redundancy of sensorial power; and in inflammatory diseases with arterial strength, there is an excess of both.

Hence if the sensorial power be lessened, while the quant.i.ty of stimulus remains the same as in nervous fever, the frequency of repet.i.tion of the arterial contractions may continue, but their force in respect to removing obstacles, as in promoting the circulation of the blood, or the velocity of each contraction, will be diminished, that is, the animal strength will be lessened. And secondly, if the quant.i.ty of sensorial power be lessened, and the stimulus be increased to a certain degree, as in giving opium in nervous fevers, the arterial contractions may be performed more frequently than natural, yet with less strength.

And thirdly, if the sensorial power continues the same in respect to quant.i.ty, and the stimulus be somewhat diminished, as in going into a darkish room, or into a coldish bath, suppose of about eighty degrees of heat, as Buxton-bath, a temporary weakness of the affected fibres is induced, till an acc.u.mulation of sensorial power gradually succeeds, and counterbalances the deficiency of stimulus, and then the bath ceases to feel cold, and the room ceases to appear dark; because the fibres of the subcutaneous vessels, or of the organs of sense, act with their usual energy.

A set of muscular fibres may thus be stimulated into violent exertion, that is, they may act frequently, and with their whole sensorial power, but may nevertheless not act strongly; because the quant.i.ty of their sensorial power was originally small, or was previously exhausted. Hence a stimulus may be great, and the irritation in consequence act with its full force, as in the hot paroxysms of nervous fever; but if the sensorial power, termed irritation, be small in quant.i.ty, the force of the fibrous contractions, and the times of their continuance in their contracted state, will be proportionally small.

In the same manner in the hot paroxysm of putrid fevers, which are shewn in Sect. x.x.xIII. to be inflammatory fevers with arterial debility, the sensorial power termed sensation is exerted with great activity, yet the fibrous contractions, which produce the circulation of the blood, are performed without strength, because the quant.i.ty of sensorial power then residing in that part of the system is small.

Thus in irritative fever with arterial strength, that is, with excess of spirit of animation, the quant.i.ty of exertion during the hot part of the paroxysm is to be estimated from the quant.i.ty of stimulus, and the quant.i.ty of sensorial power. While in sensitive (or inflammatory) fever with arterial strength, that is, with excess of spirit of animation, the violent and forcible actions of the vascular system during the hot part of the paroxysm are induced by the exertions of two sensorial powers, which are excited by two kinds of stimulus. These are the sensorial power of irritation excited by the stimulus of bodies external to the moving fibres, and the sensorial power of sensation excited by the pain in consequence of the increased contractions of those moving fibres.

And in insane people in some cases the force of their muscular actions will be in proportion to the quant.i.ty of sensorial power, which they possess, and the quant.i.ty of the stimulus of desire or aversion, which excites their volition into action. At the same time in other cases the stimulus of pain or pleasure, and the stimulus of external bodies, may excite into action the sensorial powers of sensation and irritation, and thus add greater force to their muscular actions.

2. The application of the stimulus, whether that stimulus be some quality of external bodies, or pleasure or pain, or desire or aversion, or a link of a.s.sociation, excites the correspondent sensorial power into action, and this causes the contraction of the fibre. On the contraction of the fibre a part of the spirit of animation becomes expended, and the fibre ceases to contract, though the stimulus continues to be applied; till in a certain time the fibre having received a supply of sensorial power is ready to contract again, if the stimulus continues to be applied. If the stimulus on the contrary be withdrawn, the same quant.i.ty of quiescent sensorial power becomes resident in the fibre as before its contraction; as appears from the readiness for action of the large locomotive muscles of the body in a short time after common exertion.