"Can I help?"

I let out an identical sigh, and made a helpless gesture. I had one vague glimmering of an idea-or rather, the return of an idea I'd had in the back of my mind for some time.

"The only thing I can think of doing is to open the leg-cut down deep through the muscle-and pour what penicillin I have left directly into the wounds. It's much more effective against bacterial infections if you can inject it, rather than give it orally. Raw penicillin like this"-I nodded at the bottle-"is very unstable in the presence of acid. It's not likely enough would make it through the stomach to do any good."

"That's more or less what Aunt Jenny did, isn't it? That's what made that huge scar on his thigh."

I nodded, wiping my palms unobtrusively over my knees. I didn't normally suffer from sweaty hands, but the feel of the amputation saw was much too clear in my memory.

"I'd have to do two or three deep cuts. It would likely cripple him permanently-but it might work." I tried to give her a smile. "I don't suppose MIT taught you how to engineer a hypodermic syringe, did they?"

"Why didn't you say so before?" she said calmly. "I don't know if I can make a syringe, but I'd be really surprised if I can't figure out something that does the same thing. How long have we got?"

I stared at her, my mouth half open, then shut it with a snap.

"A few hours, at least. I thought if we didn't get any improvement with the hot poultices, I'd have to either cut or amputate by this evening."

"Amputate!" All the blood drained out of her face. "You can't do that!"

"I can-but my God, I don't want to." My hands curled hard, denying their skill.

"Let me think, then." Her face was still pale, but the shock was passing as her mind began to focus. "Oh-where's Mrs. Bug? I was going to leave Jemmy with her, but-"

"She's gone? Are you sure she isn't just out in the hencoop?"

"No, I stopped there when I came up to the house. I didn't see her anywhere-and the kitchen fire is smoored."

That was more than odd; Mrs. Bug had come to the house as usual to make breakfast-what could have induced her to leave again? I hoped Arch hadn't suddenly been taken ill; that would just about put the cocked hat on things.

"Where's Jemmy, then?" I asked, looking round for him. He didn't normally go far away from his mother, though he was beginning to wander a bit, as small boys did.

"Lizzie took him upstairs to see Da. I'll ask her to look after him for a while."

"Fine. Oh!"

My exclamation made her turn back at the door, eyebrows raised in question.

"Do you think you could take that"-I gestured distastefully at the big glass jar-"outside, darling? Dispose of it somewhere?"

"Sure. What is it?" Curious, she walked over to the jar. The little rattlesnake had crawled out of its bag and was coiled up in a suspicious dark knot; as she extended a hand toward the jar, it lunged, striking at the glass, and Brianna jumped back with a yelp.

"Ifrinn!" she said, and I laughed, in spite of the general stress and worry. she said, and I laughed, in spite of the general stress and worry.

"Where did you get him, and what is he for?" she asked. Recovering from the initial shock, she leaned forward cautiously and tapped lightly on the glass. The snake, who appeared irascible in the extreme, struck the side of the jar with an audible thump, and she jerked her hand away again.

"Kezzie brought him in; Jamie is meant to drink his blood as a cure," I explained.

She reached out a cautious forefinger, and traced the path of a small droplet of yellowish liquid, sliding down the glass. Two droplets, in fact.

"Look at that! He tried to bite me right through the glass! That's a really mad snake; I guess he doesn't think much of the idea."

He didn't. He-if it was a he-was coiled again, tiny rattles vibrating in an absolute frenzy of animosity.

"Well, that's all right," I said, coming to stand beside her. "I'm sure Jamie wouldn't think much of the idea, either. He's rather strongly anti-snake at the moment."

"Mmphm." She was still staring at the little snake, a slight frown drawing down her thick red brows. "Did Kezzie say where he got it?"

"I didn't think to ask. Why?"

"It's getting cold out-snakes hibernate, don't they? In dens?"

"Well, Dr. Brickell says they do," I replied, rather dubiously. The good doctor's Natural History of North Carolina Natural History of North Carolina made entertaining reading, but I took leave to doubt some of his observations, particularly those pertaining to snakes and crocodiles, of whose prowess he appeared to have a rather exaggerated opinion. made entertaining reading, but I took leave to doubt some of his observations, particularly those pertaining to snakes and crocodiles, of whose prowess he appeared to have a rather exaggerated opinion.

She nodded, not taking her eyes off the snake.

"See, the thing is," she said, sounding rather dreamy, "pit-vipers have beautiful engineering. Their jaws are disarticulated, so they can swallow prey bigger than they are-and their fangs fold back against the roof of their mouth when they aren't using them."

"Yes?" I said, giving her a slightly fishy look, which she ignored.

"The fangs are hollow," she said, and touched a finger to the glass, marking the spot where the venom had soaked into the linen cloth, leaving a small yellowish stain. "They're connected to a venom sac in the snake's cheek, and so when they bite down, the cheek muscles squeeze venom out of the sac ... and down through the fang into the prey. Just like a-"

"Jesus H. Roosevelt Christ," I said.

She nodded, finally taking her eyes off the snake in order to look at me.

"I was thinking of trying to do something with a sharpened quill, but this would work lots better-it's already designed for the job."

"I see," I said, feeling a small surge of hope. "But you'll need a reservoir of some kind ..."

"First I need a bigger snake," she said practically, turning toward the door. "Let me go find Jo or Kezzie, and see if that one did did come from a den-and if so, if there are more of them there." come from a den-and if so, if there are more of them there."

She set off promptly on this mission, taking the glass jar with her, and leaving me to return to a contemplation of the antibiotic situation with renewed hope. If I was going to be able to inject the solution, it needed to be strained and purified as much as possible.

I would have liked to boil the solution, but didn't dare to; I didn't know whether high temperatures would destroy or inactivate raw penicillin-if, in fact, there still was was active penicillin in there. The surge of hope I had experienced at Brianna's idea dimmed somewhat. Having a hypodermic apparatus wouldn't help, if I had nothing useful to inject. active penicillin in there. The surge of hope I had experienced at Brianna's idea dimmed somewhat. Having a hypodermic apparatus wouldn't help, if I had nothing useful to inject.

Restlessly, I moved around the surgery, picking things up and putting them down again.

Steeling myself, I put my hand on the saw again, and closed my eyes, deliberately reliving the movements and sensations, trying also to recapture the sense of otherworldly detachment with which I had killed the buffalo.

Of course, it was Jamie who'd been talking to the otherworld this time. Nice of you to give him the choice Nice of you to give him the choice, I thought sardonically. I see you aren't going to make it easy on him, though. I see you aren't going to make it easy on him, though.

But he wouldn't have asked for that. I opened my eyes, startled. I didn't know whether that answer came from my own subconscious, or elsewhere-but there it was in my mind, and I recognized the truth of it.

Jamie was accustomed to make his choice and abide by it, no matter the cost. He saw that living would likely mean the loss of his leg and all that that implied-and had accepted that as the natural price of his decision.

"Well, I don't bloody accept it!" I said out loud, chin uplifted toward the window. A cedar waxwing swinging on the end of a tree limb gave me a sharp look through his black robber's mask, decided I was mad but harmless, and went about his business.

I pulled open the cupboard door, threw open the top of my medicine chest, and fetched a sheet of paper, quill, and ink from Jamie's study.

A jar of dried red wintergreen berries. Extract of pipsissewa. Slippery elm bark. Willow bark, cherry bark, fleabane, yarrow. Penicillin was by far the most effective of the antibiotics available, but it wasn't the only one. People had been waging war on germs for thousands of years, without any notion what they were fighting. I knew; that was some slight advantage.

I began to make a list of the herbs I had on hand, and under each name, all the uses that I knew for that herb-whether I had ever made such use of it or not. Any herb used to treat a septic condition was a possibility-cleansing lacerations, treating mouth sores, treatment of diarrhea and dysentery ... I heard footsteps in the kitchen, and called to Mrs. Bug, wanting her to bring me a kettle of boiling water, so I could set things to steeping at once.

She appeared in the doorway, her cheeks bright pink from the cold and her hair coming down in untidy wisps from under her kerch, a large basket clutched in her arms. Before I could say anything, she came and plunked the basket down on the counter in front of me. Just behind her came her husband, with another basket, and a small open keg, from which came a pungent alcoholic scent. The air around them held a faint ripe smell, like the distant reek of a garbage dump.

"I did hear ye say as how ye'd not enough mold on hand," she started in, anxious but bright-eyed, "so I said to Arch, I said, we must go round to the houses nearabouts, and see what we can fetch back wi' us for Mrs. Fraser, for after all, bread does go bad so quick when it's damp, and the good Lord kens that Mrs. Chisholm is a slattern, for all I'm sure she's a good heart, and what goings-on there may be at her hearth I'm sure I shouldna like even to think think about, but we-" about, but we-"

I wasn't paying attention, but was staring at the results of the Bugs' morning raid on the pantries and middens of the Ridge. Crusts of bread, spoilt biscuit, half-rotted squash, bits of pie with the marks of teeth still visible in the pastry ... a hodgepodge of gluey orts and decaying fragments-all sprouting molds in patches of velvet-blue and lichen-green, interspersed with warty blobs of pink and yellow and dustings of splotchy white. The keg was half-filled with decaying corn, the resultant murky liquid rimmed with floating islands of blue mold.

"Evan Lindsay's pigs," Mr. Bug explained, in a rare burst of loquacity. Both Bugs beamed at me, begrimed with their efforts.

"Thank you," I said, feeling choked, and not only from the smell. I blinked, eyes watering slightly from the miasma of the corn liquor. "Oh, thank you."

IT WAS JUST AFTER DARK when I made my way upstairs, carrying my tray of potions and implements, feeling a mixture of excitement and trepidation.

Jamie was propped on his pillows, surrounded by visitors. People had been coming by the house all day to see him and wish him well; a good many of them had simply stayed, and a host of anxious faces turned toward me as I came in, glimmering in the light of the candles.

He looked very ill, flushed and drawn, and I wondered whether I ought to have chased the visitors away. I saw Murdo Lindsay take his hand, though, and squeeze it tight, and realized that the distraction and support of his company through the day was probably much more helpful to him than the rest that he wouldn't have taken in any case.

"Well, then," Jamie said, with a good assumption of casualness, "we're ready, I suppose." He stretched his legs, flexing his toes hard under the blanket. Given the state of his leg, it must have hurt dreadfully, but I recognized that he was taking what he thought would be the last opportunity to move the limb, and bit the inside of my lip.

"Well, we're ready to have a go at something," I said, smiling at him with an attempt at confident reassurance. "And anyone who would like to pray about it, please do."

A rustle of surprise replaced the air of dread that had been sprung up at my appearance, and I saw Marsali, who was holding a sleeping Joan with one hand, grope hastily in her pocket with the other to pull out her rosary.

There was a rush to clear the bedside table, which was littered with books, papers, candle-stubs, various treats brought up to tempt Jamie's appetite-all untouched-and, for some unfathomable reason, the fret-board of a dulcimer and a half-tanned groundhog hide. I set down the tray, and Brianna, who had come up with me, stepped forward, her invention carefully held in both hands, like an acolyte presenting bread to a priest.

"What in the name of Christ is that?" Jamie frowned at the object, then up at me.

"It's sort of a do-it-yourself rattlesnake," Brianna told him.

Everyone murmured with interest, craning their necks to see-though the interest was diverted almost at once as I turned back the quilt and began to unwrap his leg, to a chorus of shocked murmurs and sympathetic exclamations at sight of it.

Lizzie and Marsali had been faithfully applying fresh, hot onion and flaxseed poultices to it all day, and wisps of steam rose from the wrappings as I put them aside. The flesh of his leg was bright red to the knee, at least in those parts that weren't black or seeping with pus. We had removed the maggots temporarily, afraid the heat would kill them; they were presently downstairs on a plate in my surgery, happily occupied with some of the nastier bits of the Bugs' gleanings. If I succeeded in saving the leg, they could help with the tidying-up, later.

I had carefully gone through the detritus bit by bit, examining the blue molds with my microscope, and putting aside everything that could be identified as bearing Penicillium Penicillium into a large bowl. Over this miscellaneous collection I had poured the fermented corn liquor, allowing the whole to steep during the day-and with luck, to dissolve any actual raw penicillin from the garbage into the alcoholic liquid. into a large bowl. Over this miscellaneous collection I had poured the fermented corn liquor, allowing the whole to steep during the day-and with luck, to dissolve any actual raw penicillin from the garbage into the alcoholic liquid.

Meanwhile, I had made a selection of those herbs with a reputation for the internal treatment of suppurative conditions, and made a stiff decoction of them, steeped in boiling water for several hours. I poured a cup of this highly aromatic solution, and handed it to Roger, carefully averting my nose.

"Make him drink it," I said. "All of it," I added pointedly, fixing Jamie with a look.

Jamie sniffed the proffered cup, and gave me the look back-but obediently sipped, making exaggerated faces for the entertainment of his company, who giggled appreciatively. The mood thus lightened, I proceeded to the main event, turning to take the makeshift hypodermic from Bree.

The Beardsley twins, standing shoulder-to-shoulder in the corner, pressed forward to see, swelling with pride. They had gone out at once at Bree's request, coming back in mid-afternoon with a fine rattlesnake, nearly three feet long-and fortunately dead, having been cut nearly in half with an ax, so as to preserve the valuable head.

I had dissected out the poison sacs with great caution, detaching the fangs, and then had put Mrs. Bug to the task of rinsing the fangs repeatedly with alcohol, to eradicate any lingering traces of venom.

Bree had taken the oiled silk that had been used to wrap the astrolabe, and stitched part of it into a small tube, gathering one end of this with a draw-stitch, like a purse-string. She had cut a thick segment from a turkey's wing-quill, softened with hot water, and used this to join the gathered end of the silk tube to the fang. Melted beeswax had sealed the joints of tube, quill, and fang, and been spread carefully along the line of the stitching, to prevent leakage. It was a nice, neat job-but it did did look quite like a small, fat snake with one enormous curved fang, and occasioned no little comment from the spectators. look quite like a small, fat snake with one enormous curved fang, and occasioned no little comment from the spectators.

Murdo Lindsay was still holding one of Jamie's hands. As I motioned to Fergus to hold the candle for me, I saw Jamie reach out the other toward Roger. Roger looked momentarily startled, but grabbed the hand and knelt down by the bed, holding on tight.

I ran my fingers lightly over the leg, selected a good spot, clear of major blood vessels, swabbed it with pure alcohol, and jabbed the fang in, as deeply as I could. There was a gasp from the spectators, and a sharp intake of breath from Jamie, but he didn't move.

"All right." I nodded at Brianna, who was standing by with the bottle of strained corn-alcohol. Teeth sunk in her lower lip, she poured carefully, filling the silk tube as I supported it. I folded the open top tightly over, and with thumb and forefinger, firmly pressed downward, forcing the liquid out through the fang and into the tissues of the leg.

Jamie made a small, breathless noise, and both Murdo and Roger leaned inward instinctively, their shoulders pressing against his, holding on.

I didn't dare go too fast, for fear of cracking the wax seals by exerting too much pressure, though we had a second syringe, made with the other fang, just in case. I worked my way up and down the leg, with Bree refilling the syringe with each injection, and blood rose glistening from the holes as I withdrew the fang, rolling in tiny rivulets down the side of his leg. Without being asked, Lizzie picked up a cloth and blotted it clean, eyes intent on the job.

The room was silent, but I felt everyone's breath held as I chose a new spot, let out in a sigh as the stab was made-and then the unconscious leaning toward the bed as I squeezed the stinging alcohol deep into the infected tissues. The muscles stood out in knots on Jamie's forearms, and sweat ran down his face like rain, but neither he, nor Murdo, nor Roger made a sound or moved.

From the corner of my eye, I saw Joseph Wemyss stroke back the hair from Jamie's forehead, and wipe away the sweat from his face and neck with a towel.

"Because ye need me," he'd said. And I realized then that it wasn't only me that he'd meant. he'd said. And I realized then that it wasn't only me that he'd meant.

It didn't take a long time. When it was done, I spread honey carefully over all the open wounds, and rubbed oil of wintergreen into the skin of foot and calf.

"That's a nice job of basting, Sassenach. D'ye reckon it's ready for the oven yet?" Jamie asked, and wiggled his toes, causing the tension in the room to relax into laughter.

Everyone did leave, then, patting Jamie's shoulder or kissing his cheek in farewell, with gruff wishes of good luck. He smiled and nodded, lifting his hand in farewell, exchanging goodbyes, making small jokes.

When the door closed behind the last of them, he lay back on the pillow and closed his eyes, letting all his breath out in a long, deep sigh. I set about tidying my tray, setting the syringe to soak in alcohol, corking bottles, folding bandages. Then I sat down beside him, and he reached out a hand to me, not opening his eyes.

His skin was warm and dry, the hand reddened from Murdo's fierce grip. I traced his knuckles gently with my thumb, listening to the rumble and clatter of the house below, subdued but lively.

"It will work," I said softly, after a minute. "I know it will."

"I know," he said. He took a deep breath, and at last, began to weep.

94

NEW BLOOD

ROGER WOKE ABRUPTLY, out of a black and dreamless sleep. He felt like a landed fish, jerked gasping into an alien and unimagined element. He saw but did not grasp his surroundings; strange light and flattened surfaces. Then his mind made sense of Brianna's touch on his arm, and he was once more inside his skin, and in a bed.

"Hwh?" He sat up suddenly, making a hoarse noise of inquiry.