The Iatrophysical school (also called iatromathematical, iatromechanical, or physiatric) was founded on theories of physiology, probably by Borelli, of Naples (1608-1679), although Sanctorius; Sanctorius, a professor at Padua, was a precursor, if not directly interested in establishing it. Sanctorius discovered the fact that an "insensible perspiration" is being given off by the body continually, and was amazed to find that loss of weight in this way far exceeded the loss of weight by all other excretions of the body combined. He made this discovery by means of a peculiar weighing-machine to which a chair was attached, and in which he spent most of his time. Very naturally he overestimated the importance of this discovery, but it was, nevertheless, of great value in pointing out the hygienic importance of the care of the skin. He also introduced a thermometer which he advocated as valuable in cases of fever, but the instrument was probably not his own invention, but borrowed from his friend Galileo.

Harvey's discovery of the circulation of the blood laid the foundation of the Iatrophysical school by showing that this vital process was comparable to a hydraulic system. In his On the Motive of Animals, Borelli first attempted to account for the phenomena of life and diseases on these principles. The iatromechanics held that the great cause of disease is due to different states of elasticity of the solids of the body interfering with the movements of the fluids, which are themselves subject to changes in density, one or both of these conditions continuing to cause stagnation or congestion. The school thus founded by Borelli was the outcome of the unbounded enthusiasm, with its accompanying exaggeration of certain phenomena with the corresponding belittling of others that naturally follows such a revolutionary discovery as that of Harvey. Having such a founder as the brilliant Italian Borelli, it was given a sufficient impetus by his writings to carry it some distance before it finally collapsed. Some of the exaggerated mathematical calculations of Borelli himself are worth noting. Each heart-beat, as he calculated it, overcomes a resistance equal to one hundred and eighty thousand pounds;--the modern physiologist estimates its force at from five to nine ounces!

THOMAS SYDENHAM

But while the Continent was struggling with these illusive "systems,"

and dabbling in mystic theories that were to scarcely outlive the men who conceived them, there appeared in England--the "land of common-sense," as a German scientist has called it--"a cool, clear, and unprejudiced spirit," who in the golden age of systems declined "to be like the man who builds the chambers of the upper story of his house before he had laid securely the foundation walls."(1) This man was Thomas Sydenham (1624-1689), who, while the great Harvey was serving the king as surgeon, was fighting as a captain in the parliamentary army.

Sydenham took for his guide the teachings of Hippocrates, modified to suit the advances that had been made in scientific knowledge since the days of the great Greek, and established, as a standard, observation and experience. He cared little for theory unless confirmed by practice, but took the Hippocratic view that nature cured diseases, a.s.sisted by the physician. He gave due credit, however, to the importance of the part played by the a.s.sistant. As he saw it, medicine could be advanced in three ways: (1) "By accurate descriptions or natural histories of diseases; (2) by establishing a fixed principle or method of treatment, founded upon experience; (3) by searching for specific remedies, which he believes must exist in considerable numbers, though he admits that the only one yet discovered is Peruvian bark."(2) As it happened, another equally specific remedy, mercury, when used in certain diseases, was already known to him, but he evidently did not recognize it as such.

The influence on future medicine of Sydenham's teachings was most p.r.o.nounced, due mostly to his teaching of careful observation. To most physicians, however, he is now remembered chiefly for his introduction of the use of laudanum, still considered one of the most valuable remedies of modern pharmacopoeias. The German gives the honor of introducing this preparation to Paracelsus, but the English-speaking world will always believe that the credit should be given to Sydenham.

IX. PHILOSOPHER-SCIENTISTS AND NEW INSt.i.tUTIONS OF LEARNING

We saw that in the old Greek days there was no sharp line of demarcation between the field of the philosopher and that of the scientist. In the h.e.l.lenistic epoch, however, knowledge became more specialized, and our recent chapters have shown us scientific investigators whose efforts were far enough removed from the intangibilities of the philosopher. It must not be overlooked, however, that even in the present epoch there were men whose intellectual efforts were primarily directed towards the subtleties of philosophy, yet who had also a penchant for strictly scientific imaginings, if not indeed for practical scientific experiments. At least three of these men were of sufficient importance in the history of the development of science to demand more than pa.s.sing notice. These three are the Englishman Francis Bacon (1561-1626), the Frenchman Rene Descartes (1596-1650); and the German Gottfried Leibnitz (1646-1716). Bacon, as the earliest path-breaker, showed the way, theoretically at least, in which the sciences should be studied; Descartes, pursuing the methods pointed out by Bacon, carried the same line of abstract reason into practice as well; while Leibnitz, coming some years later, and having the advantage of the wisdom of his two great predecessors, was naturally influenced by both in his views of abstract scientific principles.

Bacon's career as a statesman and his faults and misfortunes as a man do not concern us here. Our interest in him begins with his entrance into Trinity College, Cambridge, where he took up the study of all the sciences taught there at that time. During the three years he became more and more convinced that science was not being studied in a profitable manner, until at last, at the end of his college course, he made ready to renounce the old Aristotelian methods of study and advance his theory of inductive study. For although he was a great admirer of Aristotle's work, he became convinced that his methods of approaching study were entirely wrong.

"The opinion of Aristotle," he says, in his De Argumentum Scientiarum, "seemeth to me a negligent opinion, that of those things which exist by nature nothing can be changed by custom; using for example, that if a stone be thrown ten thousand times up it will not learn to ascend; and that by often seeing or hearing we do not learn to see or hear better.

For though this principle be true in things wherein nature is peremptory (the reason whereof we cannot now stand to discuss), yet it is otherwise in things wherein nature admitteth a lat.i.tude. For he might see that a straight glove will come more easily on with use; and that a wand will by use bend otherwise than it grew; and that by use of the voice we speak louder and stronger; and that by use of enduring heat or cold we endure it the better, and the like; which latter sort have a nearer resemblance unto that subject of manners he handleth than those instances which he allegeth."(1)

These were his opinions, formed while a young man in college, repeated at intervals through his maturer years, and reiterated and emphasized in his old age. Ma.s.ses of facts were to be obtained by observing nature at first hand, and from such acc.u.mulations of facts deductions were to be made. In short, reasoning was to be from the specific to the general, and not vice versa.

It was by his teachings alone that Bacon thus contributed to the foundation of modern science; and, while he was constantly thinking and writing on scientific subjects, he contributed little in the way of actual discoveries. "I only sound the clarion," he said, "but I enter not the battle."

The case of Descartes, however, is different. He both sounded the clarion and entered into the fight. He himself freely acknowledges his debt to Bacon for his teachings of inductive methods of study, but modern criticism places his work on the same plane as that of the great Englishman. "If you lay hold of any characteristic product of modern ways of thinking," says Huxley, "either in the region of philosophy or in that of science, you find the spirit of that thought, if not its form, has been present in the mind of the great Frenchman."(2)

Descartes, the son of a n.o.ble family of France, was educated by Jesuit teachers. Like Bacon, he very early conceived the idea that the methods of teaching and studying science were wrong, but be pondered the matter well into middle life before putting into writing his ideas of philosophy and science. Then, in his Discourse Touching the Method of Using One's Reason Rightly and of Seeking Scientific Truth, he pointed out the way of seeking after truth. His central idea in this was to emphasize the importance of DOUBT, and avoidance of accepting as truth anything that does not admit of absolute and unqualified proof. In reaching these conclusions he had before him the striking examples of scientific deductions by Galileo, and more recently the discovery of the circulation of the blood by Harvey. This last came as a revelation to scientists, reducing this seemingly occult process, as it did, to the field of mechanical phenomena. The same mechanical laws that governed the heavenly bodies, as shown by Galileo, governed the action of the human heart, and, for aught any one knew, every part of the body, and even the mind itself.

Having once conceived this idea, Descartes began a series of dissections and experiments upon the lower animals, to find, if possible, further proof of this general law. To him the human body was simply a machine, a complicated mechanism, whose functions were controlled just as any other piece of machinery. He compared the human body to complicated machinery run by water-falls and complicated pipes. "The nerves of the machine which I am describing," he says, "may very well be compared to the pipes of these waterworks; its muscles and its tendons to the other various engines and springs which seem to move them; its animal spirits to the water which impels them, of which the heart is the fountain; while the cavities of the brain are the central office. Moreover, respiration and other such actions as are natural and usual in the body, and which depend on the course of the spirits, are like the movements of a clock, or a mill, which may be kept up by the ordinary flow of water."(3)

In such pa.s.sages as these Descartes antic.i.p.ates the ideas of physiology of the present time. He believed that the functions are performed by the various organs of the bodies of animals and men as a mechanism, to which in man was added the soul. This soul he located in the pineal gland, a degenerate and presumably functionless little organ in the brain. For years Descartes's idea of the function of this gland was held by many physiologists, and it was only the introduction of modern high-power microscopy that reduced this also to a mere mechanism, and showed that it is apparently the remains of a Cyclopean eye once common to man's remote ancestors.

Descartes was the originator of a theory of the movements of the universe by a mechanical process--the Cartesian theory of vortices--which for several decades after its promulgation reigned supreme in science. It is the ingenuity of this theory, not the truth of its a.s.sertions, that still excites admiration, for it has long since been supplanted. It was certainly the best hitherto advanced--the best "that the observations of the age admitted," according to D'Alembert.

According to this theory the infinite universe is full of matter, there being no such thing as a vacuum. Matter, as Descartes believed, is uniform in character throughout the entire universe, and since motion cannot take place in any part of a s.p.a.ce completely filled, without simultaneous movement in all other parts, there are constant more or less circular movements, vortices, or whirlpools of particles, varying, of course, in size and velocity. As a result of this circular movement the particles of matter tend to become globular from contact with one another. Two species of matter are thus formed, one larger and globular, which continue their circular motion with a constant tendency to fly from the centre of the axis of rotation, the other composed of the clippings resulting from the grinding process. These smaller "filings"

from the main bodies, becoming smaller and smaller, gradually lose their velocity and acc.u.mulate in the centre of the vortex. This collection of the smaller matter in the centre of the vortex const.i.tutes the sun or star, while the spherical particles propelled in straight lines from the centre towards the circ.u.mference of the vortex produce the phenomenon of light radiating from the central star. Thus this matter becomes the atmosphere revolving around the acc.u.mulation at the centre. But the small particles being constantly worn away from the revolving spherical particles in the vortex, become entangled in their pa.s.sage, and when they reach the edge of the inner strata of solar dust they settle upon it and form what we call sun-spots. These are constantly dissolved and reformed, until sometimes they form a crust round the central nucleus.

As the expansive force of the star diminishes in the course of time, it is encroached upon by neighboring vortices. If the part of the encroaching star be of a less velocity than the star which it has swept up, it will presently lose its hold, and the smaller star pa.s.s out of range, becoming a comet. But if the velocity of the vortex into which the incrusted star settles be equivalent to that of the surrounded vortex, it will hold it as a captive, still revolving and "wrapt in its own firmament." Thus the several planets of our solar system have been captured and held by the sun-vortex, as have the moon and other satellites.

But although these new theories at first created great enthusiasm among all cla.s.ses of philosophers and scientists, they soon came under the ban of the Church. While no actual harm came to Descartes himself, his writings were condemned by the Catholic and Protestant churches alike.

The spirit of philosophical inquiry he had engendered, however, lived on, and is largely responsible for modern philosophy.

In many ways the life and works of Leibnitz remind us of Bacon rather than Descartes. His life was spent in filling high political positions, and his philosophical and scientific writings were by-paths of his fertile mind. He was a theoretical rather than a practical scientist, his contributions to science being in the nature of philosophical reasonings rather than practical demonstrations. Had he been able to withdraw from public life and devote himself to science alone, as Descartes did, he would undoubtedly have proved himself equally great as a practical worker. But during the time of his greatest activity in philosophical fields, between the years 1690 and 1716, he was all the time performing extraordinary active duties in entirely foreign fields.

His work may be regarded, perhaps, as doing for Germany in particular what Bacon's did for England and the rest of the world in general.

Only a comparatively small part of his philosophical writings concern us here. According to his theory of the ultimate elements of the universe, the entire universe is composed of individual centres, or monads. To these monads he ascribed numberless qualities by which every phase of nature may be accounted. They were supposed by him to be percipient, self-acting beings, not under arbitrary control of the deity, and yet G.o.d himself was the original monad from which all the rest are generated. With this conception as a basis, Leibnitz deduced his doctrine of pre-established harmony, whereby the numerous independent substances composing the world are made to form one universe. He believed that by virtue of an inward energy monads develop themselves spontaneously, each being independent of every other. In short, each monad is a kind of deity in itself--a microcosm representing all the great features of the macrocosm.

It would be impossible clearly to estimate the precise value of the stimulative influence of these philosophers upon the scientific thought of their time. There was one way, however, in which their influence was made very tangible--namely, in the incentive they gave to the foundation of scientific societies.

SCIENTIFIC SOCIETIES

At the present time, when the elements of time and distance are practically eliminated in the propagation of news, and when cheap printing has minimized the difficulties of publishing scientific discoveries, it is difficult to understand the isolated position of the scientific investigation of the ages that preceded steam and electricity. Shut off from the world and completely out of touch with fellow-laborers perhaps only a few miles away, the investigators were naturally seriously handicapped; and inventions and discoveries were not made with the same rapidity that they would undoubtedly have been had the same men been receiving daily, weekly, or monthly communications from fellow-laborers all over the world, as they do to-day. Neither did they have the advantage of public or semi-public laboratories, where they were brought into contact with other men, from whom to gather fresh trains of thought and receive the stimulus of their successes or failures. In the natural course of events, however, neighbors who were interested in somewhat similar pursuits, not of the character of the rivalry of trade or commerce, would meet more or less frequently and discuss their progress. The mutual advantages of such intercourse would be at once appreciated; and it would be but a short step from the casual meeting of two neighborly scientists to the establishment of "societies," meeting at fixed times, and composed of members living within reasonable travelling distance. There would, perhaps, be the weekly or monthly meetings of men in a limited area; and as the natural outgrowth of these little local societies, with frequent meetings, would come the formation of larger societies, meeting less often, where members travelled a considerable distance to attend. And, finally, with increased facilities for communication and travel, the great international societies of to-day would be produced--the natural outcome of the neighborly meetings of the primitive mediaeval investigators.

In Italy, at about the time of Galileo, several small societies were formed. One of the most important of these was the Lyncean Society, founded about the year 1611, Galileo himself being a member. This society was succeeded by the Accademia del Cimento, at Florence, in 1657, which for a time flourished, with such a famous scientist as Torricelli as one of its members.

In England an impetus seems to have been given by Sir Francis Bacon's writings in criticism and censure of the system of teaching in colleges. It is supposed that his suggestions as to what should be the aims of a scientific society led eventually to the establishment of the Royal Society. He pointed out how little had really been accomplished by the existing inst.i.tutions of learning in advancing science, and a.s.serted that little good could ever come from them while their methods of teaching remained unchanged. He contended that the system which made the lectures and exercises of such a nature that no deviation from the established routine could be thought of was pernicious. But he showed that if any teacher had the temerity to turn from the traditional paths, the daring pioneer was likely to find insurmountable obstacles placed in the way of his advancement. The studies were "imprisoned" within the limits of a certain set of authors, and originality in thought or teaching was to be neither contemplated nor tolerated.

The words of Bacon, given in strong and unsparing terms of censure and condemnation, but nevertheless with perfect justification, soon bore fruit. As early as the year 1645 a small company of scientists had been in the habit of meeting at some place in London to discuss philosophical and scientific subjects for mental advancement. In 1648, owing to the political disturbances of the time, some of the members of these meetings removed to Oxford, among them Boyle, Wallis, and Wren, where the meetings were continued, as were also the meetings of those left in London. In 1662, however, when the political situation bad become more settled, these two bodies of men were united under a charter from Charles II., and Bacon's ideas were practically expressed in that learned body, the Royal Society of London. And it matters little that in some respects Bacon's views were not followed in the practical workings of the society, or that the division of labor in the early stages was somewhat different than at present. The aim of the society has always been one for the advancement of learning; and if Bacon himself could look over its records, he would surely have little fault to find with the aid it has given in carrying out his ideas for the promulgation of useful knowledge.

Ten years after the charter was granted to the Royal Society of London, Lord Bacon's words took practical effect in Germany, with the result that the Academia Naturae Curiosorum was founded, under the leadership of Professor J. C. Sturm. The early labors of this society were devoted to a repet.i.tion of the most notable experiments of the time, and the work of the embryo society was published in two volumes, in 1672 and 1685 respectively, which were practically text-books of the physics of the period. It was not until 1700 that Frederick I. founded the Royal Academy of Sciences at Berlin, after the elaborate plan of Leibnitz, who was himself the first president.

Perhaps the nearest realization of Bacon's ideal, however, is in the Royal Academy of Sciences at Paris, which was founded in 1666 under the administration of Colbert, during the reign of Louis XIV. This inst.i.tution not only recognized independent members, but had besides twenty pensionnaires who received salaries from the government. In this way a select body of scientists were enabled to pursue their investigations without being obliged to "give thought to the morrow"

for their sustenance. In return they were to furnish the meetings with scientific memoirs, and once a year give an account of the work they were engaged upon. Thus a certain number of the brightest minds were encouraged to devote their entire time to scientific research, "delivered alike from the temptations of wealth or the embarra.s.sments of poverty." That such a plan works well is amply attested by the results emanating from the French academy. Pensionnaires in various branches of science, however, either paid by the state or by learned societies, are no longer confined to France.

Among the other early scientific societies was the Imperial Academy of Sciences at St. Petersburg, projected by Peter the Great, and established by his widow, Catharine I., in 1725; and also the Royal Swedish Academy, incorporated in 1781, and counting among its early members such men as the celebrated Linnaeus. But after the first impulse had resulted in a few learned societies, their manifest advantage was so evident that additional numbers increased rapidly, until at present almost every branch of every science is represented by more or less important bodies; and these are, individually and collectively, adding to knowledge and stimulating interest in the many fields of science, thus vindicating Lord Bacon's a.s.severations that knowledge could be satisfactorily promulgated in this manner.

X. THE SUCCESSORS OF GALILEO IN PHYSICAL SCIENCE

We have now to witness the diversified efforts of a company of men who, working for the most part independently, greatly added to the data of the physical sciences--such men as Boyle, Huygens, Von Gericke, and Hooke. It will be found that the studies of these men covered the whole field of physical sciences as then understood--the field of so-called natural philosophy. We shall best treat these successors of Galileo and precursors of Newton somewhat biographically, pointing out the correspondences and differences between their various accomplishments as we proceed. It will be noted in due course that the work of some of them was antic.i.p.atory of great achievements of a later century.

ROBERT BOYLE (1627-1691)

Some of Robert Boyle's views as to the possible structure of atmospheric air will be considered a little farther on in this chapter, but for the moment we will take up the consideration of some of his experiments upon that as well as other gases. Boyle was always much interested in alchemy, and carried on extensive experiments in attempting to accomplish the trans.m.u.tation of metals; but he did not confine himself to these experiments, devoting himself to researches in all the fields of natural philosophy. He was a.s.sociated at Oxford with a company of scientists, including Wallis and Wren, who held meetings and made experiments together, these gatherings being the beginning, as mentioned a moment ago, of what finally became the Royal Society. It was during this residence at Oxford that many of his valuable researches upon air were made, and during this time be invented his air-pump, now exhibited in the Royal Society rooms at Burlington House.(1)

His experiments to prove the atmospheric pressure are most interesting and conclusive. "Having three small, round gla.s.s bubbles, blown at the flame of a lamp, about the size of hazel-nuts," he says, "each of them with a short, slender stem, by means whereof they were so exactly poised in water that a very small change of weight would make them either emerge or sink; at a time when the atmosphere was of convenient weight, I put them into a wide-mouthed gla.s.s of common water, and leaving them in a quiet place, where they were frequently in my eye, I observed that sometimes they would be at the top of the water, and remain there for several days, or perhaps weeks, together, and sometimes fall to the bottom, and after having continued there for some time rise again. And sometimes they would rise or fall as the air was hot or cold."(2)

It was in the course of these experiments that the observations made by Boyle led to the invention of his "statical barometer," the mercurial barometer having been invented, as we have seen, by Torricelli, in 1643.

In describing this invention he says: "Making choice of a large, thin, and light gla.s.s bubble, blown at the flame of a lamp, I counterpoised it with a metallic weight, in a pair of scales that were suspended in a frame, that would turn with the thirtieth part of a grain. Both the frame and the balance were then placed near a good barometer, whence I might learn the present weight of the atmosphere; when, though the scales were unable to show all the variations that appeared in the mercurial barometer, yet they gave notice of those that altered the height of the mercury half a quarter of an inch."(3) A fairly sensitive barometer, after all. This statical barometer suggested several useful applications to the fertile imagination of its inventor, among others the measuring of mountain-peaks, as with the mercurial barometer, the rarefication of the air at the top giving a definite ratio to the more condensed air in the valley.

Another of his experiments was made to discover the atmospheric pressure to the square inch. After considerable difficulty he determined that the relative weight of a cubic inch of water and mercury was about one to fourteen, and computing from other known weights he determined that "when a column of quicksilver thirty inches high is sustained in the barometer, as it frequently happens, a column of air that presses upon an inch square near the surface of the earth must weigh about fifteen avoirdupois pounds."(4) As the pressure of air at the sea-level is now estimated at 14.7304 pounds to the square inch, it will be seen that Boyle's calculation was not far wrong.

From his numerous experiments upon the air, Boyle was led to believe that there were many "latent qualities" due to substances contained in it that science had as yet been unable to fathom, believing that there is "not a more heterogeneous body in the world." He believed that contagious diseases were carried by the air, and suggested that eruptions of the earth, such as those made by earthquakes, might send up "venomous exhalations" that produced diseases. He suggested also that the air might play an important part in some processes of calcination, which, as we shall see, was proved to be true by Lavoisier late in the eighteenth century. Boyle's notions of the exact chemical action in these phenomena were of course vague and indefinite, but he had observed that some part was played by the air, and he was right in supposing that the air "may have a great share in varying the salts obtainable from calcined vitriol."(5)

Although he was himself such a painstaking observer of facts, he had the fault of his age of placing too much faith in hear-say evidence of untrained observers. Thus, from the numerous stories he heard concerning the growth of metals in previously exhausted mines, he believed that the air was responsible for producing this growth--in which he undoubtedly believed. The story of a tin-miner that, in his own time, after a lapse of only twenty-five years, a heap, of earth previously exhausted of its ore became again even more richly impregnated than before by lying exposed to the air, seems to have been believed by the philosopher.

As Boyle was an alchemist, and undoubtedly believed in the alchemic theory that metals have "spirits" and various other qualities that do not exist, it is not surprising that he was credulous in the matter of beliefs concerning peculiar phenomena exhibited by them. Furthermore, he undoubtedly fell into the error common to "specialists," or persons working for long periods of time on one subject--the error of over-enthusiasm in his subject. He had discovered so many remarkable qualities in the air that it is not surprising to find that he attributed to it many more that he could not demonstrate.

Boyle's work upon colors, although probably of less importance than his experiments and deductions upon air, show that he was in the van as far as the science of his day was concerned. As he points out, the schools of his time generally taught that "color is a penetrating quality, reaching to the innermost part of the substance," and, as an example of this, sealing-wax was cited, which could be broken into minute bits, each particle retaining the same color as its fellows or the original ma.s.s. To refute this theory, and to show instances to the contrary, Boyle, among other things, shows that various colors--blue, red, yellow--may be produced upon tempered steel, and yet the metal within "a hair's-breadth of its surface" have none of these colors. Therefore, he was led to believe that color, in opaque bodies at least, is superficial.

"But before we descend to a more particular consideration of our subject," he says, "'tis proper to observe that colors may be regarded either as a quality residing in bodies to modify light after a particular manner, or else as light itself so modified as to strike upon the organs of sight, and cause the sensation we call color; and that this latter is the more proper acceptation of the word color will appear hereafter. And indeed it is the light itself, which after a certain manner, either mixed with shades or other-wise, strikes our eyes and immediately produces that motion in the organ which gives us the color of an object."(6)