In the light of after events, it is probable that Wharton's stock as an astrologer was not greatly enhanced by this doc.u.ment, at least among members of the Royal family. Lilly's book, on the other hand, became a favorite with the Parliamentary army.

After the downfall and death of Napoleon there were unearthed many alleged authentic astrological doc.u.ments foretelling his ruin. And on the death of George IV., in 1830, there appeared a doc.u.ment (unknown, as usual, until that time) purporting to foretell the death of the monarch to the day, and this without the astrologer knowing that his horoscope was being cast for a monarch. A full account of this prophecy is told, with full belief, by Roback, a nineteenth-century astrologer. He says:

"In the year 1828, a stranger of n.o.ble mien, advanced in life, but possessing the most bland manners, arrived at the abode of a celebrated astrologer in London," asking that the learned man foretell his future.

"The astrologer complied with the request of the mysterious visitor, drew forth his tables, consulted his ephemeris, and cast the horoscope or celestial map for the hour and the moment of the inquiry, according to the established rules of his art.

"The elements of his calculation were adverse, and a feeling of gloom cast a shade of serious thought, if not dejection, over his countenance.

"'You are of high rank,' said the astrologer, as he calculated and looked on the stranger, 'and of ill.u.s.trious t.i.tle.' The stranger made a graceful inclination of the head in token of acknowledgment of the complimentary remarks, and the astrologer proceeded with his mission.

"The celestial signs were ominous of calamity to the stranger, who, probably observing a sudden change in the countenance of the astrologer, eagerly inquired what evil or good fortune had been a.s.signed him by the celestial orbs.

"'To the first part of your inquiry,' said the astrologer, 'I can readily reply. You have been a favorite of fortune; her smiles on you have been abundant, her frowns but few; you have had, perhaps now possess, wealth and power; the impossibility of their accomplishment is the only limit to the fulfilment of your desires.'"

"'You have spoken truly of the past,' said the stranger. 'I have full faith in your revelations of the future: what say you of my pilgrimage in this life--is it short or long?'

"'I regret,' replied the astrologer, in answer to this inquiry, 'to be the herald of ill, though TRUE, fortune; your sojourn on earth will be short.'

"'How short?' eagerly inquired the excited and anxious stranger.

"'Give me a momentary truce,' said the astrologer; 'I will consult the horoscope, and may possibly find some mitigating circ.u.mstances.'

"Having cast his eyes over the celestial map, and paused for some moments, he surveyed the countenance of the stranger with great sympathy, and said, 'I am sorry that I can find no planetary influences that oppose your destiny--your death will take place in two years.'

"The event justified the astrologic prediction: George IV. died on May 18, 1830, exactly two years from the day on which he had visited the astrologer."(8)

This makes a very pretty story, but it hardly seems like occult insight that an astrologer should have been able to predict an early death of a man nearly seventy years old, or to have guessed that his well-groomed visitor "had, perhaps now possesses, wealth and power." Here again, however, the point of view of each individual plays the governing part in determining the importance of such a doc.u.ment. To the scientist it proves nothing; to the believer in astrology, everything. The significant thing is that it appeared shortly AFTER the death of the monarch.

On the Continent astrologers were even more in favor than in England.

Charlemagne, and some of his immediate successors, to be sure, attempted to exterminate them, but such rulers as Louis XI. and Catherine de'

Medici patronized and encouraged them, and it was many years after the time of Copernicus before their influence was entirely stamped out even in official life. There can be no question that what gave the color of truth to many of the predictions was the fact that so many of the prophecies of sudden deaths and great conflagrations were known to have come true--in many instances were made to come true by the astrologer himself. And so it happened that when the prediction of a great conflagration at a certain time culminated in such a conflagration, many times a second but less-important burning took place, in which the ambitious astrologer, or his followers, took a central part about a stake, being convicted of incendiarism, which they had committed in order that their prophecies might be fulfilled.

But, on the other hand, these predictions were sometimes turned to account by interested friends to warn certain persons of approaching dangers.

For example, a certain astrologer foretold the death of Prince Alexander de' Medici. He not only foretold the death, but described so minutely the circ.u.mstances that would attend it, and gave such a correct description of the a.s.sa.s.sin who should murder the prince, that he was at once suspected of having a hand in the a.s.sa.s.sination. It developed later, however, that such was probably not the case; but that some friend of Prince Alexander, knowing of the plot to take his life, had induced the astrologer to foretell the event in order that the prince might have timely warning and so elude the conspirators.

The cause of the decline of astrology was the growing prevalence of the new spirit of experimental science. Doubtless the most direct blow was dealt by the Copernican theory. So soon as this was established, the recognition of the earth's subordinate place in the universe must have made it difficult for astronomers to be longer deceived by such coincidences as had sufficed to convince the observers of a more credulous generation. Tycho Brahe was, perhaps, the last astronomer of prominence who was a conscientious practiser of the art of the astrologer.

VII. FROM PARACELSUS TO HARVEY

PARACELSUS

In the year 1526 there appeared a new lecturer on the platform at the University at Basel--a small, beardless, effeminate-looking person--who had already inflamed all Christendom with his peculiar philosophy, his revolutionary methods of treating diseases, and his unparalleled success in curing them. A man who was to be remembered in after-time by some as the father of modern chemistry and the founder of modern medicine; by others as madman, charlatan, impostor; and by still others as a combination of all these. This soft-cheeked, effeminate, woman-hating man, whose very s.e.x has been questioned, was Theophrastus von Hohenheim, better known as Paracelsus (1493-1541).

To appreciate his work, something must be known of the life of the man.

He was born near Maria-Einsiedeln, in Switzerland, the son of a poor physician of the place. He began the study of medicine under the instruction of his father, and later on came under the instruction of several learned churchmen. At the age of sixteen he entered the University of Basel, but, soon becoming disgusted with the philosophical teachings of the time, he quitted the scholarly world of dogmas and theories and went to live among the miners in the Tyrol, in order that he might study nature and men at first hand. Ordinary methods of study were thrown aside, and he devoted his time to personal observation--the only true means of gaining useful knowledge, as he preached and practised ever after. Here he became familiar with the art of mining, learned the physical properties of minerals, ores, and metals, and acquired some knowledge of mineral waters. More important still, he came in contact with such diseases, wounds, and injuries as miners are subject to, and he tried his hand at the practical treatment of these conditions, untrammelled by the traditions of a profession in which his training had been so scant.

Having acquired some empirical skill in treating diseases, Paracelsus set out wandering from place to place all over Europe, gathering practical information as he went, and learning more and more of the medicinal virtues of plants and minerals. His wanderings covered a period of about ten years, at the end of which time he returned to Basel, where he was soon invited to give a course of lectures in the university.

These lectures were revolutionary in two respects--they were given in German instead of time-honored Latin, and they were based upon personal experience rather than upon the works of such writers as Galen and Avicenna. Indeed, the iconoclastic teacher spoke with open disparagement of these revered masters, and openly upbraided his fellow-pract.i.tioners for following their tenets. Naturally such teaching raised a storm of opposition among the older physicians, but for a time the unparalleled success of Paracelsus in curing diseases more than offset his unpopularity. Gradually, however, his bitter tongue and his coa.r.s.e personality rendered him so unpopular, even among his patients, that, finally, his liberty and life being jeopardized, he was obliged to flee from Basel, and became a wanderer. He lived for brief periods in Colmar, Nuremberg, Appenzell, Zurich, Pfeffers, Augsburg, and several other cities, until finally at Salzburg his eventful life came to a close in 1541. His enemies said that he had died in a tavern from the effects of a protracted debauch; his supporters maintained that he had been murdered at the instigation of rival physicians and apothecaries.

But the effects of his teachings had taken firm root, and continued to spread after his death. He had shown the fallibility of many of the teachings of the hitherto standard methods of treating diseases, and had demonstrated the advantages of independent reasoning based on observation. In his Magic.u.m he gives his reasons for breaking with tradition. "I did," he says, "embrace at the beginning these doctrines, as my adversaries (followers of Galen) have done, but since I saw that from their procedures nothing resulted but death, murder, stranglings, anchylosed limbs, paralysis, and so forth, that they held most diseases incurable.... therefore have I quitted this wretched art, and sought for truth in any other direction. I asked myself if there were no such thing as a teacher in medicine, where could I learn this art best? Nowhere better than the open book of nature, written with G.o.d's own finger." We shall see, however, that this "book of nature" taught Paracelsus some very strange lessons. Modesty was not one of these. "Now at this time,"

he declares, "I, Theophrastus Paracelsus, Bombast, Monarch of the Arcana, was endowed by G.o.d with special gifts for this end, that every searcher after this supreme philosopher's work may be forced to imitate and to follow me, be he Italian, Pole, Gaul, German, or whatsoever or whosoever he be. Come hither after me, all ye philosophers, astronomers, and spagirists.... I will show and open to you... this corporeal regeneration."(1)

Paracelsus based his medical teachings on four "pillars"--philosophy, astronomy, alchemy, and virtue of the physician--a strange-enough equipment surely, and yet, properly interpreted, not quite so anomalous as it seems at first blush. Philosophy was the "gate of medicine,"

whereby the physician entered rightly upon the true course of learning; astronomy, the study of the stars, was all-important because "they (the stars) caused disease by their exhalations, as, for instance, the sun by excessive heat"; alchemy, as he interpreted it, meant the improvement of natural substances for man's benefit; while virtue in the physician was necessary since "only the virtuous are permitted to penetrate into the innermost nature of man and the universe."

All his writings aim to promote progress in medicine, and to hold before the physician a grand ideal of his profession. In this his views are wide and far-reaching, based on the relationship which man bears to nature as a whole; but in his sweeping condemnations he not only rejected Galenic therapeutics and Galenic anatomy, but condemned dissections of any kind. He laid the cause of all diseases at the door of the three mystic elements--salt, sulphur, and mercury. In health he supposed these to be mingled in the body so as to be indistinguishable; a slight separation of them produced disease; and death he supposed to be the result of their complete separation. The spiritual agencies of diseases, he said, had nothing to do with either angels or devils, but were the spirits of human beings.

He believed that all food contained poisons, and that the function of digestion was to separate the poisonous from the nutritious. In the stomach was an archaeus, or alchemist, whose duty was to make this separation. In digestive disorders the archaeus failed to do this, and the poisons thus gaining access to the system were "coagulated" and deposited in the joints and various other parts of the body. Thus the deposits in the kidneys and tartar on the teeth were formed; and the stony deposits of gout were particularly familiar examples of this. All this is visionary enough, yet it shows at least a groping after rational explanations of vital phenomena.

Like most others of his time, Paracelsus believed firmly in the doctrine of "signatures"--a belief that every organ and part of the body had a corresponding form in nature, whose function was to heal diseases of the organ it resembled. The vagaries of this peculiar doctrine are too numerous and complicated for lengthy discussion, and varied greatly from generation to generation. In general, however, the theory may be summed up in the words of Paracelsus: "As a woman is known by her shape, so are the medicines." Hence the physicians were constantly searching for some object of corresponding shape to an organ of the body. The most natural application of this doctrine would be the use of the organs of the lower animals for the treatment of the corresponding diseased organs in man. Thus diseases of the heart were to be treated with the hearts of animals, liver disorders with livers, and so on. But this apparently simple form of treatment had endless modifications and restrictions, for not all animals were useful. For example, it was useless to give the stomach of an ox in gastric diseases when the indication in such cases was really for the stomach of a rat. Nor were the organs of animals the only "signatures" in nature. Plants also played a very important role, and the herb-doctors devoted endless labor to searching for such plants.

Thus the blood-root, with its red juice, was supposed to be useful in blood diseases, in stopping hemorrhage, or in subduing the redness of an inflammation.

Paracelsus's system of signatures, however, was so complicated by his theories of astronomy and alchemy that it is practically beyond comprehension. It is possible that he himself may have understood it, but it is improbable that any one else did--as shown by the endless discussions that have taken place about it. But with all the vagaries of his theories he was still rational in his applications, and he attacked to good purpose the complicated "shot-gun" prescriptions of his contemporaries, advocating more simple methods of treatment.

The ever-fascinating subject of electricity, or, more specifically, "magnetism," found great favor with him, and with properly adjusted magnets he claimed to be able to cure many diseases. In epilepsy and lockjaw, for example, one had but to fasten magnets to the four extremities of the body, and then, "when the proper medicines were given," the cure would be effected. The easy loop-hole for excusing failure on the ground of improper medicines is obvious, but Paracelsus declares that this one prescription is of more value than "all the humoralists have ever written or taught."

Since Paracelsus condemned the study of anatomy as useless, he quite naturally regarded surgery in the same light. In this he would have done far better to have studied some of his predecessors, such as Galen, Paul of Aegina, and Avicenna. But instead of "cutting men to pieces," he taught that surgeons would gain more by devoting their time to searching for the universal panacea which would cure all diseases, surgical as well as medical. In this we detect a taint of the popular belief in the philosopher's stone and the magic elixir of life, his belief in which have been stoutly denied by some of his followers. He did admit, however, that one operation alone was perhaps permissible--lithotomy, or the "cutting for stone."

His influence upon medicine rests undoubtedly upon his revolutionary att.i.tude, rather than on any great or new discoveries made by him. It is claimed by many that he brought prominently into use opium and mercury, and if this were indisputably proven his services to medicine could hardly be overestimated. Unfortunately, however, there are good grounds for doubting that he was particularly influential in reintroducing these medicines. His chief influence may perhaps be summed up in a single phrase--he overthrew old traditions.

To Paracelsus's endeavors, however, if not to the actual products of his work, is due the credit of setting in motion the chain of thought that developed finally into scientific chemistry. Nor can the ultimate aim of the modern chemist seek a higher object than that of this sixteenth-century alchemist, who taught that "true alchemy has but one aim and object, to extract the quintessence of things, and to prepare arcana, tinctures, and elixirs which may restore to man the health and soundness he has lost."

THE GREAT ANATOMISTS

About the beginning of the sixteenth century, while Paracelsus was scoffing at the study of anatomy as useless, and using his influence against it, there had already come upon the scene the first of the great anatomists whose work was to make the century conspicuous in that branch of medicine.

The young anatomist Charles etienne (1503-1564) made one of the first noteworthy discoveries, pointing out for the first time that the spinal cord contains a ca.n.a.l, continuous throughout its length. He also made other minor discoveries of some importance, but his researches were completely overshadowed and obscured by the work of a young Fleming who came upon the scene a few years later, and who shone with such brilliancy in the medical world that he obscured completely the work of his contemporary until many years later. This young physician, who was destined to lead such an eventful career and meet such an untimely end as a martyr to science, was Andrew Vesalius (1514-1564), who is called the "greatest of anatomists." At the time he came into the field medicine was struggling against the dominating Galenic teachings and the theories of Paracelsus, but perhaps most of all against the superst.i.tions of the time. In France human dissections were attended with such dangers that the young Vesalius transferred his field of labors to Italy, where such investigations were covertly permitted, if not openly countenanced.

From the very start the young Fleming looked askance at the accepted teachings of the day, and began a series of independent investigations based upon his own observations. The results of these investigations he gave in a treatise on the subject which is regarded as the first comprehensive and systematic work on human anatomy. This remarkable work was published in the author's twenty-eighth or twenty-ninth year. Soon after this Vesalius was invited as imperial physician to the court of Emperor Charles V. He continued to act in the same capacity at the court of Philip II., after the abdication of his patron. But in spite of this royal favor there was at work a factor more powerful than the influence of the monarch himself--an instrument that did so much to r.e.t.a.r.d scientific progress, and by which so many lives were brought to a premature close.

Vesalius had received permission from the kinsmen of a certain grandee to perform an autopsy. While making his observations the heart of the outraged body was seen to palpitate--so at least it was reported. This was brought immediately to the attention of the Inquisition, and it was only by the intervention of the king himself that the anatomist escaped the usual fate of those accused by that tribunal. As it was, he was obliged to perform a pilgrimage to the Holy Land. While returning from this he was shipwrecked, and perished from hunger and exposure on the island of Zante.

At the very time when the anatomical writings of Vesalius were startling the medical world, there was living and working contemporaneously another great anatomist, Eustachius (died 1574), whose records of his anatomical investigations were ready for publication only nine years after the publication of the work of Vesalius. Owing to the unfortunate circ.u.mstances of the anatomist, however, they were never published during his lifetime--not, in fact, until 1714. When at last they were given to the world as Anatomical Engravings, they showed conclusively that Eustachius was equal, if not superior to Vesalius in his knowledge of anatomy. It has been said of this remarkable collection of engravings that if they had been published when they were made in the sixteenth century, anatomy would have been advanced by at least two centuries.

But be this as it may, they certainly show that their author was a most careful dissector and observer.

Eustachius described accurately for the first time certain structures of the middle ear, and rediscovered the tube leading from the ear to the throat that bears his name. He also made careful studies of the teeth and the phenomena of first and second dent.i.tion. He was not baffled by the minuteness of structures and where he was unable to study them with the naked eye he used gla.s.ses for the purpose, and resorted to macerations and injections for the study of certain complicated structures. But while the fruit of his pen and pencil were lost for more than a century after his death, the effects of his teachings were not; and his two pupils, Fallopius and Columbus, are almost as well known to-day as their ill.u.s.trious teacher. Columbus (1490-1559) did much in correcting the mistakes made in the anatomy of the bones as described by Vesalius. He also added much to the science by giving correct accounts of the shape and cavities of the heart, and made many other discoveries of minor importance. Fallopius (1523-1562) added considerably to the general knowledge of anatomy, made several discoveries in the anatomy of the ear, and also several organs in the abdominal cavity.

At this time a most vitally important controversy was in progress as to whether or not the veins of the bodies were supplied with valves, many anatomists being unable to find them. Etienne had first described these structures, and Vesalius had confirmed his observations. It would seem as if there could be no difficulty in settling the question as to the fact of such valves being present in the vessels, for the demonstration is so simple that it is now made daily by medical students in all physiological laboratories and dissecting-rooms. But many of the great anatomists of the sixteenth century were unable to make this demonstration, even when it had been brought to their attention by such an authority as Vesalius. Fallopius, writing to Vesalius on the subject in 1562, declared that he was unable to find such valves. Others, however, such as Eustachius and Fabricius (1537-1619), were more successful, and found and described these structures. But the purpose served by these valves was entirely misinterpreted. That they act in preventing the backward flow of the blood in the veins on its way to the heart, just as the valves of the heart itself prevent regurgitation, has been known since the time of Harvey; but the best interpretation that could be given at that time, even by such a man as Fabricius, was that they acted in r.e.t.a.r.ding the flow of the blood as it comes from the heart, and thus prevent its too rapid distribution throughout the body.

The fact that the blood might have been going towards the heart, instead of coming from it, seems never to have been considered seriously until demonstrated so conclusively by Harvey.

Of this important and remarkable controversy over the valves in veins, Withington has this to say: "This is truly a marvellous story. A great Galenic anatomist is first to give a full and correct description of the valves and their function, but fails to see that any modification of the old view as to the motion of the blood is required. Two able dissectors carefully test their action by experiment, and come to a result, the exact reverse of the truth. Urged by them, the two foremost anatomists of the age make a special search for valves and fail to find them.

Finally, pa.s.sing over lesser peculiarities, an aged and honorable professor, who has lived through all this, calmly a.s.serts that no anatomist, ancient or modern, has ever mentioned valves in veins till he discovered them in 1574!"(2)